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Seung-Kyung Hann, James Nordlund

Datos Técnicos

Notas del Editor

This monograph is a comprehensive expose of the disorder vitiligo. The book introduces the topic with a presentation about its cultural effects in the Middle East where vitiligo is exceptionally disabling to the affected person. Nehru as Prime Minister of India stated that vitiligo was a major impediment to the successful development of India. The book includes sections on the definition of vitiligo based on a consensus of world experts on vitiligo. There is a complete description of its clinical manifestations including the extracutaneous sites by world experts. Differentiation of vitiligo from other forms of depigmentation associated with malignancies is included with sufficient photographs to document differences. A section will present the physiological changes associated with depigmentation - a little known phenomena. The complete histology, differential diagnosis and animal models are major sections. The animal models are important in formulating theories about the causes of vitiligo. Most clinicians will find this section very informative. The book finishes with a thorough treatise on the principles of therapy.

Contenido

- List of Contributors
- Foreword
- Preface

- Part 1: General Topics about Vitiligo

1. Definition of Vitiligo
2. The Loss of Melanocytes from the Epidermis: the Mechanism for Depigmentation of Vitiligo Vulgaris
3. History and Cultural Aspects of Vitiligo
4. Genetics and Prevalence of Vitiligo Vulgaris

- Part 2: Clinical Presentation of Vitiligo

5. Histology of Vitiliginous Skin
6. Clinical Features of Generalized Vitiligo
7. Clinical Features of Segmental Vitiligo
8. Childhood Vitiligo: Clinical Spectrum and Therapeutic Approaches
9. Special Features of Vitiligo
10. Depigmentation of Hair and Mucous Membranes
11. Ocular and Otic Findings in Vitiligo
12. The Association of Vitiligo with Disorders of Other Organ Systems
13. The Psychological Effects of Vitiligo: Response to Impaired Appearance
14. Differential Diagnosis of Vitiligo Vulgaris

- Part 3. Pathogenesis of Vitiligo: Theories for Depigmentation

15. The Intrinsic (Genetic) Theory for the Cause of Vitiligo
16. Theories on the Pathogenesis of Depigmentation: Immune Hypothesis
17. Autocytotoxic Hypothesis for the Destruction of Melanocytes as the Cause of Vitiligo
18. Neural Pathogenesis
19. Biochemical Theory of Vitiligo: A Role of Pteridines in Pigmentation

- Part 4: Treatment of Vitiligo

20. The Melanocyte Reservoir and its Necessity
21. PUVA Therapy
22. Steroid Treatment for Vitiligo
23. Pseudocatalase in the Treatment of Vitiligo
24. Surgical Therapies for Vitiligo
25. Micropigmentation
26. Depigmentation for the Treatment of Extensive Vitiligo
27. Ancillary Therapies: Helping the Patient with Vitiligo to Adjust
28. Sunscreens and Sun Protection
29. Alternative Therapies for Vitiligo

- Part 5: Topics Related to Vitiligo

30. Depigmentation Other Than Vitiligo
31. Physiological Alterations in the Depigmented Skin of Patients with Vitiligo
32. Chemical Leukoderma
33. Animal Models

- Index

Contacto

Editorial: Blackwell Science, Inc.